Anthropogenic disturbances to nitrogen (N) cycling, particularly through agricultural N use, have intensified nitrous oxide (N2O) emissions. Developing wheat lines with biological nitrification inhibition (BNI) is a promising strategy to reduce such emissions. However, the effectiveness of BNI depends not only on plant characteristics, but also on how they interact with environmental factors such as […]

Abstract Schistosomiasis remains a major communicable disease of public health and socioeconomic importance in developing countries. This cross-sectional study assessed the prevalence of Schistosoma haematobium infection among basic schoolchildren in Al Thawra Mobi Village, Wad Madani Alkobra Locality, Gezira State, Sudan. A total of 272 participants (208 boys and 64 girls) were enrolled. Urine samples […]

The architecture of Mycobacterium tuberculosis (Mtb) biofilms, associated with phenotypic drug tolerance, is poorly defined. Here, we reveal that these biofilms are highly organized corded superstructures, and in deconstructing their architecture, we provide a new molecular understanding of cording itself. Using multimodal imaging, we demonstrate that a functional amyloid matrix provides the fundamental structural integrity […]

Background Maternal anemia remains a significant public health challenge in Nigeria, affecting approximately 25-46% of pregnant women and contributing to adverse maternal and neonatal outcomes. Intravenous (IV) iron provides a promising alternative to conventional oral iron supplementation for managing moderate to severe maternal anemia; however, its implementation in resource-limited settings faces numerous challenges. This study […]

Ezrin is a peripheral membrane protein that contributes to the organization and stability of cellular membrane structures by reversibly linking the plasma membrane to actin filaments. The formation of this membrane-actin linkage has been experimentally shown to require ezrin N-terminal (FERM) domain binding to PI(4,5)P2 phospholipid-enriched membrane sites and the phosphorylation of the ezrin Cterminal […]

Background: Chronic lung allograft dysfunction (CLAD) leads to declining respiratory function and high mortality, representing the main barrier to long-term survival in lung transplantation (LT). We performed the first genome-wide association study (GWAS) investigating donor and recipient genetic factors associated with CLAD. Method: We genotyped 392 donor-recipient pairs from the multicentric Cohort in Lung Transplantation. […]

Pantoea stewartii subsp. stewartii (Pss), the causal agent of Stewart’s wilt in maize, is native to North America but has been detected on several occasions also in Europe, including in Italy in association with seed maize production. These findings have raised concern due to the bacterium’s quarantine status in the EU. To investigate its diversity […]

The spread of the highly invasive mosquito, Aedes albopictus, across Europe, combined with climate change and human travel and trade, has led to new epidemic threats from mosquito-borne viruses, most significantly dengue and chikungunya, which are increasing in frequency and magnitude. In 2025, mainland France has seen a record number of autochthonous cases and outbreaks […]

Eukaryotic flagella, or motile cilia, are iconic molecular machines whose beating drives cell propulsion and fluid transport across diverse organisms. Beat type and waveform are tailored to function, differing between species and cell types, and individual flagella can switch between beat types. Aberrant beating causes ciliopathies and infertility in humans1 and prevents unicellular parasite transmission2. […]

We aimed to evaluate the efficacy and safety of a spore forming probiotic blend containing Clostridium butyricum IDCC 1301, Weizmannia coagulans IDCC 1201, and Bacillus subtilis IDCC 1101 for improving bowel function and well being in adults with functional constipation (FC). In a randomized, double blind, placebo controlled trial, 78 adults with FC (Rome IV […]