FAIR foundations of a novel indicator vault for non-communicable diseases in the European Union: feasibility study for effective contextualisation of indicators

BackgroundComparing health indicators across the European Union (EU) is a challenging endeavour. A feasibility study was conducted to explore opportunities for improvement through the contextualisation of indicators for major non-communicable diseases (NCDs). We aimed to improve the usability and transparency of indicators in the domain of NCDs by describing the contextual information about the data […]

Effectiveness of an integrated community and hospital digital health information system for maternal and newborn healthcare in Northern Kenya: a nonrandomized before-after evaluation

BackgroundPoor access to antenatal care (ANC), skilled delivery, and postnatal checks within 48 h of delivery are linked to adverse pregnancy outcomes. In Kenya, unequal use of these services has caused significant regional disparities, with 15 out of 47 counties being high priority.ObjectivesTo evaluate the effectiveness of a digital health solution to improve maternal and newborn […]

AI/ML driven prediction of COPD exacerbations and readmissions: a systematic review and meta-analysis

BackgroundChronic obstructive pulmonary disease (COPD) exacerbations and hospital readmissions are major drivers of morbidity, mortality, and healthcare costs. Artificial intelligence and machine learning (AI/ML) approaches have been applied to predict these events, but their pooled performance and methodological rigor remain unclear.MethodsFollowing PRISMA 2020 guidelines, we conducted a systematic review and meta-analysis of peer-reviewed studies developing […]

One digital health through wearables: a viewpoint on human–pet integration towards Healthcare 5.0

Wearable technologies mark a transition in healthcare evolution, from paternalistic (Healthcare 1.0) to reactive (Healthcare 2.0), proactive (Healthcare 3.0), and data-integrated care (Healthcare 4.0). The next stage, Healthcare 5.0, envisions the seamless integration of human and pet health data, fostering a more holistic approach to disease prevention and management. In this viewpoint, we explore the […]

ScolioClass: data-driven development of a new classification tool to evaluate adolescent idiopathic scoliosis optically diagnosed

Adolescent idiopathic scoliosis (AIS) is traditionally assessed and classified using radiographic methods that rely on Cobb angle measurements and qualitative curve modifiers, exposing patients to repeated radiation and offering limited sensitivity to subtle three-dimensional (3D) deformities. We developed ScolioClass, a non-invasive, data-driven classification tool that harnesses 3D optical surface scanning and continuous indices, capturing curvature […]

Artificial intelligence-based remote monitoring for chronic heart failure: design and rationale of the SMART-CARE study

IntroductionChronic heart failure (CHF) is associated with frequent hospitalizations, poor quality of life, and high healthcare costs. Despite therapeutic progress, early recognition of clinical deterioration remains difficult. The SMART-CARE study investigates whether artificial intelligence (AI)-enabled remote monitoring using CE-certified wearable devices can reduce hospital admissions and improve patient outcomes in CHF.MethodsSMART-CARE is a prospective, multicenter, […]

Impact of telehealth on health outcomes and quality of life in the older adults population: a systematic review

BackgroundThe rapid aging of populations poses major challenges to health and social care systems. Supporting older adults in managing chronic conditions while promoting independence and quality of life requires innovative approaches that extend beyond senior institutional care. Telehealth has emerged as a promising approach to enhance access, continuity, and patient engagement. However, evidence regarding its […]

Foundational digital literacy training for frontline immunization officers: lessons from implementing the electronic stock management tool across selected comprehensive health centers in Sierra Leone

BackgroundSierra Leone has advanced its digital health agenda. However, digital literacy among frontline health workers remains low, with over 82% reporting limited confidence in using digital tools. The health workforce also recorded the lowest digital health maturity score among all enablers in the WHO Global Digital Health Monitor, underscoring the need for workforce upskilling as […]

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