Novo Nordisk has won US approval of the first oral treatment for obesity in more than a decade. The Danish drugmaker’s obesity pill was approved by the FDA on Monday. It …
Threat Actors Exploit Zero-Day in WatchGuard Firebox Devices
With attacks on the critical firewall vulnerability, WatchGuard joins a list of edge device vendors that have been targeted in recent weeks.
Prognostic Prediction Models for Ulcerative Colitis: Systematic Review and Meta-Analysis
Background: Ulcerative colitis (UC) is a chronic inflammatory disease with highly variable symptoms and severity. Prognostic models for UC support precision medicine by enabling personalized treatment strategies. However, the quality and clinical utility of these models remain inadequately assessed. Objective: This study aimed to systematically review and critically evaluate the development, performance, and applicability of […]
Visualization of Experience Sampling Method Data in Mental Health: Qualitative Study of the Physicians’ Perspective in Germany
Background: Although the integration of self-monitored patient data into mental health care offers potential for advancing personalised approaches, its application in clinical practice remains largely underexplored. Capturing individuals’ mental health outside the therapy room using Experience Sampling Methods (ESM) may bridge this gap by supporting shared decision-making and personalised interventions. Objective: This qualitative study investigated […]
Barriers to and Facilitators of Implementation of Internet-Delivered Therapist-Guided Therapy in Child and Adolescent Mental Health Services: Systematic Review and Bayesian Meta-Analysis
Background: Implementation of internet-delivered therapist-guided therapy (e-therapy) can increase accessibility and resource efficiency in youth mental health services. At present, there is limited evidence to guide mental health researchers and practitioners on critical barriers and facilitators of successful e-therapy implementation in child and adolescent mental health services (CAMHS). Objective: This systematic review assesses the current […]
CMS proposes two long-awaited Medicare drug pricing demos
CMS has proposed two mandatory payment models aimed at lowering drug prices in Medicare, initiatives that build on President Donald Trump’s “most favored nation” plan but are likely to face pushback from industry. The two …
Implementation of a Mobile Digital Tool Supporting Medication for Opioid Use Disorder Treatment Improves Retention: Stepped-Wedge Cluster Randomized Controlled Trial
Background: Despite its proven efficacy, retention in medication for opioid use disorder (MOUD) remains low, with structural and systemic barriers—such as access to care and treatment setting—alongside individual factors, including personalization and motivation, contributing to high rates of discontinuation. Digital interventions offer a promising approach to address many of these barriers; however, robust evidence for […]
China’s new commercial insurance model could broaden access to Alzheimer’s drugs
China’s new commercial insurance formulary looks to expand patient access to Alzheimer’s disease medicines from Eli Lilly and Eisai while potentially boosting revenue for the companies. Announced in December, the Commercial Health Insurance Innovative Drug …
Bristol Myers brings IRA drug pricing fight to Supreme Court
Bristol Myers Squibb is the second drugmaker to take its Inflation Reduction Act challenge to the Supreme Court, arguing that the program unlawfully forces it to sell its blockbuster blood thinner Eliquis at a steep …
Tai Chi Chuan Auxiliary Training Systems in Health and Rehabilitation: Scoping Review
Background: Tai Chi Chuan (TCC), often described as “moving meditation”, is a traditional Chinese mind-body exercise suitable for individuals of all ages. Mounting evidence demonstrates that TCC can improve physical functions, promote physical activity, and positively impact health and longevity. However, systematic learning is hindered by insufficient teaching resources, difficulties in imparting expertise, and learning […]