BackgroundShort videos have become a primary channel for Lumbar Disc Herniation (LDH) patients to obtain disease knowledge and rehabilitation guidance. Algorithm-driven personalized recommendations may expose patients to heterogeneous LDH-related content, affecting their health anxiety and rehabilitation trajectories.ObjectiveThis study explored the impacts of LDH-related short video exposure duration and content types on health anxiety and lumbar […]
Health care management in Africa: a debate for future research and agenda
This article provides a critical narrative synthesis of literature on healthcare management in Africa, focusing on two interconnected areas: the impact of managerial capability on shaping integrated healthcare ecosystems and the adoption, implementation, and governance of digital health innovations within diverse health system contexts. Based on health systems strengthening frameworks and socio-technical views on digital […]
Chinese Cyber Threat Lurks In Critical Asian Sectors for Years
An undefined Chinese-speaking actor wields a combo of custom malware, open source tools, and LOTL binaries against Windows and Linux, likely for spying.
Alfasigma licenses liver drug from GSK in $590m deal
With an FDA verdict looming, GSK has signed an eleventh-hour deal to give Alfasigma rights to its primary biliary cholangitis therapy linerixibat.
Alfasigma licenses liver drug from GSK in $690m deal
With an FDA verdict looming, GSK has signed an eleventh-hour deal to give Alfasigma rights to its primary biliary cholangitis therapy linerixibat.
Roche’s oral SERD flunks phase 3 breast cancer test
Roche’s recent run of positive study results with breast cancer candidate giredestrant has come to an end with the failure of the persevERA trial.
‘SNL’ pokes fun at mysteries of Amgen’s Otezla for plaque psoriasis
The sketch show’s latest pharma ad spoof arrived during this past weekend’s episode hosted by actor Ryan Gosling, who appears in the Otezla send-up as a patient now able to shed his long sleeves after treating his plaque psoriasis with the med.
GSK licenses linerixibat for liver disease itch to Alfasigma for $300M upfront
GSK is licensing out the liver disease drug linerixibat to the Italian pharma Alfasigma for $300 million upfront, weeks ahead of the pill’s March 24 PDUFA date. The drug, which is …
Cohort profile: the Resilient Minds national study of mental health and cognitive resilience in community dwelling adults aged 18 to 93
PurposeThe Resilient Minds (ReMind) cohort was established to investigate cognitive and mental health resilience across the life course, addressing a gap in longitudinal evidence about resilience. The study collected data on traditional medical and lifestyle risk factors for chronic disease, genetics, and a range of mental health and cognitive outcomes. It also aimed to explore […]
Safety concerns prompt Ipsen to pull Tazverik from market
Ipsen is voluntarily withdrawing its EZH2 inhibitor Tazverik from sale after a clinical trial suggested a link with secondary blood cancers.
Roche’s big hope breast cancer drug fails in crucial first-line trial
Roche’s breast cancer pill, which the company recently said had the potential to become its biggest-ever selling drug, has failed in what is arguably its most important Phase 3 trial. The persevERA …
Bibliometric analysis of deep learning for surgical instrument segmentation, detection and tracking in minimally invasive surgery
BackgroundDeep learning (DL) methods for surgical video analysis have expanded rapidly in minimally invasive surgery (MIS). However, a structured bibliometric overview focused on DL-based surgical instrument segmentation, detection, and tracking is lacking. The objective of this review is to systematically map the research landscape with this focus, by examining publication trends, influential authors, institutions, and […]