arXiv:2604.04958v2 Announce Type: new Abstract: Recent work suggests that large-scale, multi-animal modeling can significantly improve neural recording analysis. However, for functional calcium traces, existing approaches remain task-specific, limiting transfer across common neuroscience objectives. To address this challenge, we propose textbfCalM, a self-supervised neural foundation model trained solely on neuronal calcium traces and adaptable to multiple […]
Invivyd launches ‘Antibodies for Any Body’ campaign with Olympic skier Lindsey Vonn
U.S. Olympic gold medal-winning athlete Lindsey Vonn is once again teaming up with infectious disease biopharma Invivyd for a new campaign centering on antibody-based treatments.
Personalized artificial intelligence based left ventricular ejection fraction and systolic dysfunction assessment
npj Digital Medicine, Published online: 08 April 2026; doi:10.1038/s41746-026-02462-3 Personalized artificial intelligence based left ventricular ejection fraction and systolic dysfunction assessment
Feasibility of social media health education plus exercise in older adults with possible sarcopenia
npj Digital Medicine, Published online: 08 April 2026; doi:10.1038/s41746-026-02585-7 Feasibility of social media health education plus exercise in older adults with possible sarcopenia
Impact of an AI prognostic tool on clinician performance in colorectal liver metastases
npj Digital Medicine, Published online: 08 April 2026; doi:10.1038/s41746-026-02606-5 Impact of an AI prognostic tool on clinician performance in colorectal liver metastases
A scoping review on using real-world data to evaluate the effectiveness of mHealth applications
npj Digital Medicine, Published online: 08 April 2026; doi:10.1038/s41746-026-02562-0 A scoping review on using real-world data to evaluate the effectiveness of mHealth applications
An End-to-End Synthetic Oncology Clinical Trial Framework Integrating Radiographic Response, Circulating Tumor DNA, Safety, and Survival for Decision-Oriented Clinical Data Science
Background: Modern oncology development depends on integrating radiographic response, molecular biomarkers, treatment exposure, safety, and survival endpoints, yet access to well-structured patient-level trial data is often limited. Methods: We developed a synthetic, literature-informed phase II randomized oncology trial framework that followed the sequence Patient [->] Data [->] Dataset [->] Analysis [->] Tables/Figures [->] Decision. A […]
Uptake and retention in HIV care among pregnant and postpartum women living with HIV under different eras of vertical transmission prevention policies in sub-Saharan Africa: a systematic review and meta-analysis
Objectives: This systematic review and meta-analysis (2010 – 2025) examines changes in uptake and retention rates among pregnant and postpartum women with HIV in sub-Saharan Africa as countries adopted Option B+ for preventing vertical transmission. Design and data sources: We searched PubMed, Embase, Cochrane Library, Scopus, and African Index Medicus from 10/2021 – 05/2025 for […]
Epidemiology of Venezuelan haemorrhagic fever in Barinas state, Venezuela
Background Venezuelan haemorrhagic fever (VHF), caused by Guanarito virus (GTOV), is a zoonotic disease endemic to the western plains of Venezuela. Despite decades of recognition, its epidemiology and clinical profile remain poorly characterised. Methodology We analysed individual level data from standardised case report forms submitted to the Venezuelan National Epidemiological Surveillance System between 2017 and […]
Prespecified Internal Pilot and Feasibility Framework for a Pragmatic Randomized Controlled Trial Comparing Mechanical Diagnosis and Therapy Versus Generalized Exercise in Surgeons With Chronic Spinal Pain: A Protocol
Background Trials in occupational populations, such as surgeons, face feasibility challenges due to high workload, restricted availability, and clinical heterogeneity, which may compromise recruitment, adherence, and retention. Objective To prespecify the feasibility framework and progression criteria for an internal pilot phase embedded within a pragmatic randomized controlled trial (RCT) comparing Mechanical Diagnosis and Therapy with […]
Epigenetic Signatures in Monozygotic and Dizygotic Twins Discordant for Orofacial Clefts
Introduction: Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is a common congenital malformation with complex etiology involving both genetic and environmental factors. Epigenetic mechanisms may mediate environmental contributions, but separating genetic from environmental effects remains challenging. Methods: We present an epigenome-wide association study with 32 monozygotic and 22 dizygotic twin pairs discordant for […]
Racial and Socioeconomic Disparities in ICU Admissions Among Obstetric Patients at a Tertiary Urban Center
We aimed to evaluate disparities in perinatal ICU admissions at an urban medical center and to contextualize these findings relative to national U.S. data provided by the Centers for Disease Control and Prevention (CDC). To do so, we performed a retrospective review of all pregnant and < 6-week postpartum patients admitted to the ICU between […]