Digital mental health applications enable high-frequency behavioral monitoring and scalable interventions. Journaling provides a therapeutically grounded and intrinsically engaging activity for many users. AI-based text analysis enables privacy-preserving phenotyping of clinically relevant patterns in naturalistic writing, including emotional distress and behavioral risk (e.g., indicators of intent, planning, or preparatory actions for harm to self or […]
Cooperative molecular mimicry drives prolonged autoinflammation in multisystem inflammatory syndrome in children
Multisystem inflammatory syndrome in children (MIS-C) is a pediatric hyperinflammatory disease manifesting 4-6 weeks after SARS-CoV-2 infection. While the immunological hallmarks of MIS-C have been defined, few details regarding the underlying disease pathology have been resolved. To address this, we used a multiomics approach to profile the plasma and peripheral immune cells of 13 acute […]
The Impact of Education Level on the Risk of Heart Failure, Acute Myocardial Infarction, and Stroke in Patients with Atrial Fibrillation – a Swedish Nationwide Cohort Study
Background: Socioeconomic factors impact cardiovascular health. We investigated the association between patient education level and incident heart failure (HF), acute myocardial infarction (AMI), and stroke following a first hospitalization with atrial fibrillation (AF). Methods: In this nationwide retrospective cohort study using linked Swedish national registers, we included all patients receiving a diagnosis of AF while […]