IntroductionEarly diagnosis of dementia may be improved by objective, scalable tests that capture how cognitive tasks interfere with movement. This study examined the use of instrumented dual-task paradigms for dementia detection and characterisation.MethodsWe performed a PRISMA-guided systematic review and meta-analysis of peer-reviewed studies that used dual-task paradigms in adults with clinically defined dementia and an […]
An interpretable, clinically grounded framework for digital speech biomarker development in neurodegenerative diseases
IntroductionCommunication ability—a key determinant of quality of life—is frequently affected and progressively declines in neurodegenerative diseases. Effective management of progressive communication disorders requires a personalized approach to deliver timely interventions tailored to the evolving profiles of communicative impairment, thereby supporting functional communication throughout the disease course. To this end, reliable tools capable of detecting and […]
E-Health implementation in Pakistan: challenges, opportunities, and the path forward
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Film-based cultural narrative intervention to enhance mental health literacy and resilience in indigenous adolescents: a mixed-methods co-design study
BackgroundIndigenous adolescents in low- and middle-income countries experience heightened mental health risks while having limited access to culturally appropriate interventions. Mental health literacy, stigma, and resilience are critical determinants of help-seeking and long-term well-being, yet culturally grounded interventions addressing these factors remain scarce.ObjectiveThis study aimed to co-design and evaluate a culturally sensitive, film-based intervention to […]
Editorial: Application of computational intelligence techniques for lifestyle related diseases management
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Implementing home-based digital health in rural Canada: a scoping review
ObjectiveThis scoping review maps the current evidence on implementing home-based digital health technologies in rural Canada. It examines available readiness tools and indicators, stakeholder perspectives, barriers, and outcomes to provide evidence-based insights for successful implementation.MethodsA comprehensive search was conducted in Ovid MEDLINE, IEEE Xplore, and Scopus between February and March 2025. Eligible studies focused on […]
Barriers and facilitators to implementing an integrated electronic health records system to improve tuberculosis preventive treatment among people living with HIV: a content analysis study from Georgia
IntroductionThe integration of tuberculosis (TB) preventive treatment (TPT) into HIV services through electronic health records (EHR) can improve outcomes by enhancing care coordination, reducing redundancies, and supporting data-driven decision-making. In Georgia, despite close collaboration between TB and HIV programs, service delivery and data systems remain siloed, forcing patients to navigate between facilities and limiting the […]
Patient engagement with consumer wearable devices in the electronic health record
Data from wearable devices have the potential to transform personal health, clinical care and biomedical research. The purpose of this study was to quantify early adoption and short-term engagement with consumer-based wearable devices connected to an EHR outside of a study setting. We analyzed device data from 843 patients (mean age 48 years, 41% female) […]
Mike Guarino appointed to lead EVERSANA INTOUCH
Life sciences service provider EVERSANA has named industry veteran Mike Guarino to lead its global health agency EVERSANA INTOUCH.
Assessment of frontier Large Language Models in sleep medicine
Study objectivesTo evaluate and compare the performance of two proprietary frontier large language models (LLMs), ChatGPT-5 and Grok-4, on diagnostic reasoning and foundational knowledge tasks within the specialty domain of sleep medicine.MethodsThe models were evaluated on two tasks: case-based reasoning using 79 clinical vignettes from the AASM Case Book of Sleep Medicine and knowledge assessment […]
What’s next for IVF
Forty-eight years ago this July, Louise Joy Brown became the world’s first person born with the help of in vitro fertilization. Millions more IVF babies have entered the world since then. And that’s partly thanks to advances in technology that have made IVF safer and more effective. But it’s still not perfect. The process can […]
Angelini seeks US beachhead with $4.1bn Catalyst buy
Angelini has agreed to buy Catalyst Pharma for up to $4.1bn, its first acquisition since 2021, which would mark its entry into the US market.