Artificial intelligence (AI)–enabled systems must simultaneously improve the Quintuple Aim and digital health maturity, including equitable access to and quality and interoperability of data, tools, agents, and services. This requires a comprehensive sociotechnical and global approach to cocreation, management, and governance for individuals and organizations in the ecosystem.
EPOCA Tele-Monitoring System for Older Adults at High Risk of Hospitalization: Budget Impact and Cost-Effectiveness Analysis
Background: France’s aging population faces high rates of chronic illness, multimorbidity, and avoidable hospitalizations, placing pressure on an already strained health care system. Remote monitoring systems have shown promise in improving care coordination and reducing acute care use. Objective: The objective of this study was to assess the cost-effectiveness of the EPOCA remote monitoring system, […]
A Self-Guided App-Based Mindfulness Intervention for Racially and Ethnically Minoritized Individuals Who Experience Discrimination-Related Mental Health Symptoms: Randomized Controlled Trial
Background: Racially and ethnically minoritized individuals (REMs) who experience discrimination are at risk of developing stress, anxiety, and depression, and digital mental health interventions (DMHIs) can make evidence-based treatments such as mindfulness available to these groups. However, REMs are significantly underrepresented in the overall DMHI and mindfulness-based DMHI literature, limiting our understanding of the effectiveness […]
‘FrostyNeighbor’ APT Carefully Targets Govt Orgs in Poland, Ukraine
Attackers uniquely fingerprint victims before delivering spear-phishing payloads aimed at espionage, in the latest campaign from the Belarussian nation-state threat group.
Drugmakers have to go through rigorous tests to get a lower tariff rate
Landing a reduced 20% tariff rate will require pharma companies to fill out extensive paperwork and be closely monitored by the Department of Commerce. President Donald Trump signed an executive order last …
Trial miss doesn’t dent Biogen’s faith in Alzheimer’s drug
Biogen will advance its tau-targeting Alzheimer’s disease drug diranersen into phase 3, even though it missed the main endpoint in a midstage trial.
Degron, CREATE, TenNor raise capital; Cabaletta posts CAR-T data
💸 A Series A extension: US-China biotech Degron Therapeutics has collected an additional $40 million for its molecular glue degrader platform. The San Diego and Shanghai biotech has raised $95 million …
AstraZeneca follows Merck with Phase 3 win in bladder cancer
A combination of AstraZeneca’s Imfinzi with Pfizer and Astellas’ Padcev kept more bladder cancer patients alive than standard of care, the company said Thursday. AstraZeneca said it would seek approval for the combination, but it …
MacroGenics sells manufacturing arm; West Pharma discloses cybersecurity attack
Plus, news about Bavarian Nordic and OrganaBio’s new CDMO subsidiary: 🏭 Bora buys MacroGenics’ manufacturing operations: MacroGenics is selling its clinical and commercial drug substance production portfolio for $122.5 million upfront …
UK Health Secretary resigns, sparking leadership speculation
UK Health Secretary Wes Streeting has resigned from Keir Starmer’s government, saying he has lost faith in the Prime Minister’s leadership.
How Penn Medicine plans to use AI to train their doctors
Physicians at Penn Medicine said they’re thinking of how to use AI to train doctors. The idea came out of a $1.1 million grant Penn Medicine won in January through an education grant program with …
Establishing AI and data sovereignty in the age of autonomous systems
When generative AI first moved from research labs into real-world business applications, enterprises made a tacit bargain: “Capability now, control later.” Feed your proprietary data into third-party AI models, and you will get powerful results. But your data passes through systems you do not own, under governance you do not set. The protections you rely […]