Human Papillomavirus Vaccine Discourse and Sentiment on Reddit Before and After COVID-19: Mixed Methods Retrospective Cross-Sectional Study

Background: Human papillomavirus (HPV) is a sexually transmitted virus that causes various oropharyngeal and anogenital cancers. The HPV vaccine provides protection against several strains of HPV and is a key preventative tool against HPV-related cancers; however, vaccination rates remain suboptimal in the United States due to variable state mandates and misperceptions of vaccine efficacy and […]

Understanding Remission of Long-Term Conditions Through Electronic Health Records: Scoping Review

Background: Multiple long-term conditions (MLTCs) require complex and prolonged treatment regimens. Remission in long-term conditions (LTCs) is important for understanding disease progression and evaluating treatment effectiveness. Electronic health records (EHRs) are increasingly used to monitor clinical outcomes, but how remission is defined within EHRs remains unclear. Objective: This study aimed to summarize and collate the […]

Use of Health and Well-Being Technology, Basic Psychological Needs, and the Mediating Role of Technological Identity in 6 European Countries: Prospective Longitudinal Survey Study

Background: Digital health technologies are increasingly used to monitor and improve personal health and well-being. Simultaneously, they can influence user behavior and self-understanding. As health technologies advance and are embedded in everyday life, understanding their broader psychological impacts, as well as the role of identity in shaping these outcomes, is crucial. Objective: This prospective longitudinal […]

Nicotine Dependence and Quit Self-Confidence in a Smoking Cessation Program Using a Group-Based Digital Peer-Supported App and Cigarette Consumption–Adjusted Nicotine Aids Among Japanese Workers: Retrospective Cohort Study

Background: Completion rates for smoking cessation treatments under Japan’s national health insurance system remain suboptimal. A workplace cessation program, combining nicotine gum or patches with a group-based digital peer-supported app, has reported high cessation success rates. Although nicotine dependence is generally associated with lower cessation success, and self-confidence is generally associated with higher success, these […]

Structural Inequalities in Online Health Information Seeking: Cross-National Multilevel Study

Background: Online health information–seeking behavior (OHISB) has become an increasingly common component of contemporary health self-management. Individuals use a wide range of digital sources, including websites, social media platforms, and mobile apps, to obtain health-related information. However, substantial disparities persist in who seeks health information online, and which populations benefit from digital health resources. While […]

Co-Lifecycle Governance for Learning Medical AI: A Hybrid Convergence Framework for Adaptive Regulatory Oversight

Artificial intelligence (AI) in health care is increasingly defined not by static algorithms but by adaptive intelligence—systems that evolve over time through interactions with data, clinicians, and clinical environments. This adaptive capacity creates a structural mismatch with regulatory frameworks built for technologies whose behavior remains static. As AI models drift, recalibrate, or degrade in real-world […]

Why People Conceal Mental Health Problems: Qualitative Analysis of TikTok Posts

Background: Concealment of psychiatric symptoms is a barrier to effective mental health treatment, particularly among patients with suicidal thoughts and behaviors. Prior research on concealment has relied on retrospective self-report or laboratory-based interviews, which may not capture real-world decision-making about disclosure. Social media platforms such as TikTok provide a context in which individuals publicly narrate […]

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