FedOnco-Bench: A Reproducible Benchmark for Privacy-Aware Federated Tumor Segmentation with Synthetic CT Data

arXiv:2511.00795v1 Announce Type: cross
Abstract: Federated Learning (FL) allows multiple institutions to cooperatively train machine learning models while retaining sensitive data at the source, which has great utility in privacy-sensitive environments. However, FL systems remain vulnerable to membership-inference attacks and data heterogeneity. This paper presents FedOnco-Bench, a reproducible benchmark for privacy-aware FL using synthetic oncologic CT scans with tumor annotations. It evaluates segmentation performance and privacy leakage across FL methods: FedAvg, FedProx, FedBN, and FedAvg with DP-SGD. Results show a distinct trade-off between privacy and utility: FedAvg is high performance (Dice around 0.85) with more privacy leakage (attack AUC about 0.72), while DP-SGD provides a higher level of privacy (AUC around 0.25) at the cost of accuracy (Dice about 0.79). FedProx and FedBN offer balanced performance under heterogeneous data, especially with non-identical distributed client data. FedOnco-Bench serves as a standardized, open-source platform for benchmarking and developing privacy-preserving FL methods for medical image segmentation.