arXiv:2511.04032v1 Announce Type: new
Abstract: Multi-Agentic AI systems, powered by large language models (LLMs), are inherently non-deterministic and prone to silent failures such as drift, cycles, and missing details in outputs, which are difficult to detect. We introduce the task of anomaly detection in agentic trajectories to identify these failures and present a dataset curation pipeline that captures user behavior, agent non-determinism, and LLM variation. Using this pipeline, we curate and label two benchmark datasets comprising textbf4,275 and 894 trajectories from Multi-Agentic AI systems. Benchmarking anomaly detection methods on these datasets, we show that supervised (XGBoost) and semi-supervised (SVDD) approaches perform comparably, achieving accuracies up to 98% and 96%, respectively. This work provides the first systematic study of anomaly detection in Multi-Agentic AI systems, offering datasets, benchmarks, and insights to guide future research.
OptoLoop: An optogenetic tool to probe the functional role of genome organization
The genome folds inside the cell nucleus into hierarchical architectural features, such as chromatin loops and domains. If and how this genome organization influences the

