arXiv:2604.07549v1 Announce Type: cross
Abstract: Conversational diagnosis prediction requires models to track evolving evidence in streaming clinical conversations and decide when to commit to a diagnosis. Existing medical dialogue corpora are largely dyadic or lack the multi-party workflow and annotations needed for this setting. We introduce an ePCR-grounded, topic-flow-based multi-agent generation pipeline that iteratively plans, generates, and self-refines dialogues with rule-based factual and topic flow checks. The pipeline yields EMSDialog, a dataset of 4,414 synthetic multi-speaker EMS conversations based on a real-world ePCR dataset, annotated with 43 diagnoses, speaker roles, and turn-level topics. Human and LLM evaluations confirm high quality and realism of EMSDialog using both utterance- and conversation-level metrics. Results show that EMSDialog-augmented training improves accuracy, timeliness, and stability of EMS conversational diagnosis prediction.
Dysregulation of Hippo Signaling Pathway as a Convergent Mechanism Underlying Choroid Plexus Defects in Bipolar Disorder
Bipolar disorder (BD) is a prevalent and highly heritable psychiatric condition. Developmental mechanisms are implicated but the specific molecular origins remain unclear. The choroid plexus

