arXiv:2509.15651v2 Announce Type: replace-cross
Abstract: Assessing the impact the training data on machine learning models is crucial for understanding the behavior of the model, enhancing the transparency, and selecting training data. Influence function provides a theoretical framework for quantifying the effect of training data points on model’s performance given a specific test data. However, the computational and memory costs of influence function presents significant challenges, especially for large-scale models, even when using approximation methods, since the gradients involved in computation are as large as the model itself. In this work, we introduce a novel approach that leverages dropout as a gradient compression mechanism to compute the influence function more efficiently. Our method significantly reduces computational and memory overhead, not only during the influence function computation but also in gradient compression process. Through theoretical analysis and empirical validation, we demonstrate that our method could preserves critical components of the data influence and enables its application to modern large-scale models.
Coordinated Temporal Dynamics of Glucocorticoid Receptor Binding and Chromatin Landscape Drive Transcriptional Regulation
Glucocorticoid receptor (GR) signaling elicits diverse transcriptional responses through dynamic and context-dependent interactions with chromatin. Here, we define a temporally resolved and mechanistically integrated framework


