arXiv:2604.19406v1 Announce Type: cross
Abstract: Common image editing tasks typically adopt powerful generative diffusion models as the leading paradigm for real-world content editing. Meanwhile, although reinforcement learning (RL) methods such as Diffusion-DPO and Flow-GRPO have further improved generation quality, efficiently applying Reinforcement Learning from Human Feedback (RLHF) to diffusion-based editing remains largely unexplored, due to a lack of scalable human-preference datasets and frameworks tailored to diverse editing needs. To fill this gap, we propose HP-Edit, a post-training framework for Human Preference-aligned Editing, and introduce RealPref-50K, a real-world dataset across eight common tasks and balancing common object editing. Specifically, HP-Edit leverages a small amount of human-preference scoring data and a pretrained visual large language model (VLM) to develop HP-Scorer–an automatic, human preference-aligned evaluator. We then use HP-Scorer both to efficiently build a scalable preference dataset and to serve as the reward function for post-training the editing model. We also introduce RealPref-Bench, a benchmark for evaluating real-world editing performance. Extensive experiments demonstrate that our approach significantly enhances models such as Qwen-Image-Edit-2509, aligning their outputs more closely with human preference.
Coordinated Temporal Dynamics of Glucocorticoid Receptor Binding and Chromatin Landscape Drive Transcriptional Regulation
Glucocorticoid receptor (GR) signaling elicits diverse transcriptional responses through dynamic and context-dependent interactions with chromatin. Here, we define a temporally resolved and mechanistically integrated framework


