arXiv:2603.26948v2 Announce Type: new
Abstract: Existing approaches for predictive process monitoring are sub-symbolic, meaning that they learn correlations between descriptive features and a target feature fully based on data, e.g., predicting the surgical needs of a patient based on historical events and biometrics. However, such approaches fail to incorporate domain-specific process constraints (knowledge), e.g., surgery can only be planned if the patient was released more than a week ago, limiting the adherence to compliance and providing less accurate predictions. In this paper, we present a neuro-symbolic approach for predictive process monitoring, leveraging Logic Tensor Networks (LTNs) to inject process knowledge into predictive models. The proposed approach follows a structured pipeline consisting of four key stages: 1) feature extraction; 2) rule extraction; 3) knowledge base creation; and 4) knowledge injection. Our evaluation shows that, in addition to learning the process constraints, the neuro-symbolic model also achieves better performance, demonstrating higher compliance and improved accuracy compared to baseline approaches across all compliance-aware experiments.
Dysregulation of Hippo Signaling Pathway as a Convergent Mechanism Underlying Choroid Plexus Defects in Bipolar Disorder
Bipolar disorder (BD) is a prevalent and highly heritable psychiatric condition. Developmental mechanisms are implicated but the specific molecular origins remain unclear. The choroid plexus

