Editorial: Implementing digital twins in healthcare: pathways to person-centric solutions

Over the past decade, digital twins (DTs) have evolved from an engineering metaphor into a powerful paradigm for healthcare innovation. By dynamically linking physical and digital representations of patients, devices, and clinical processes, DTs enable continuous learning systems where data, knowledge, and decision-making converge. This transformation goes far beyond simulation: it redefines how we understand, monitor, and personalize health, moving toward predictive, preventive, personalized, and participatory (4P) medicine. The Research Topic “Implementing Digital Twins in Healthcare: Pathways to Person-Centric Solutions” brings together 8 multidisciplinary contributions that explore the translation of digital twin concepts into practical, ethical, and sustainable healthcare applications. Collectively, the works emphasize that DT implementation is not a purely technological endeavor, but rather a systemic, epistemological, and human-centered transformation of care.