The npj Digital Medicine Editorial Fellowship

npj Digital Medicine, Published online: 03 November 2025; doi:10.1038/s41746-025-02136-6 The npj Digital Medicine Editorial Fellowship ( https://www.nature.com/npjdigitalmed/editorial-fellowship ) is a year-long program that provides trainees

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The impact of confidentiality and privacy concerns on behavioral intention to adopt electronic personal health records among chronic patients in southwest Ethiopia in 2023: an application of the UTAUT2 model

BackgroundThe use of electronic personal health record systems (e-PHRS) is essential for chronic patients as they help to improve self-care management and communication between caregivers. However, when implementing e-PHRS, patients often express their concerns regarding privacy and confidentiality issues. Therefore, this study aimed to assess the impact of confidentiality and privacy concerns on the level of intention to use e-PHRS among chronic patients in southwest Ethiopia in 2023.MethodA cross-sectional study was conducted among 680 chronic patients from 24 July to 17 September 17 2023 in southwest Ethiopia. A translated interviewer-administered questionnaire was used to collect the data. A systematic random sampling approach was employed to recruit the study participants. The impact of confidentiality and privacy concerns on the patients’ intentions regarding e-PHRS adoption was examined using the extended Unified Theory of Acceptance and Use of Technology 2 (UTAUT2) model. We used measurement and structural model statistics to assess the validity of the proposed model. All the hypotheses were tested using structural equation modeling and presented using SPSS AMOS version 23. Standardized regression coefficients (β), 95% CIs, and p-values < 0.05, indicating significance, were used to examine the association between the exogenous and endogenous variables.ResultA total of 680 chronic patients, with a response rate of 87.3%, were included in the study. In total, 288 participants (42.4%) intended to adopt e-PHRS (95% CI: 39.0, 46.2). The results show that the extended UTAUT2 model explained approximately 75% of the variance in e-PHRS adoption. Confidentiality (β = 0.156, p < 0.01), privacy (β = 0.216, p < 0.05), and social influence (β = 0.157, p < 0.01) were significantly associated with adopting e-PHRS. Social influence and facilitating conditions were found to mediate confidentiality and behavioral intention, with a p-value < 0.001, while only social influence mediated the privacy concern and behavioral intention to adopt e-PHRS, with a p-value < 0.001.ConclusionLess than half of the surveyed patients intended to use e-PHRS. The result confirmed the significant impact of confidentiality and privacy concerns on e-PHRS adoption. As a result, this study demonstrates that confidentiality and privacy concerns are two main challenges that stakeholders and program developers should consider during the implementation of e-PHRS in low-income countries.

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