arXiv:2512.09572v1 Announce Type: cross
Abstract: Turbulent flows posses broadband, power-law spectra in which multiscale interactions couple high-wavenumber fluctuations to large-scale dynamics. Although diffusion-based generative models offer a principled probabilistic forecasting framework, we show that standard DDPMs induce a fundamental emphspectral collapse: a Fourier-space analysis of the forward SDE reveals a closed-form, mode-wise signal-to-noise ratio (SNR) that decays monotonically in wavenumber, $|k|$ for spectra $S(k)!propto!|k|^-lambda$, rendering high-wavenumber modes indistinguishable from noise and producing an intrinsic spectral bias. We reinterpret the noise schedule as a spectral regularizer and introduce power-law schedules $beta(tau)!propto!tau^gamma$ that preserve fine-scale structure deeper into diffusion time, along with emphLazy Diffusion, a one-step distillation method that leverages the learned score geometry to bypass long reverse-time trajectories and prevent high-$k$ degradation. Applied to high-Reynolds-number 2D Kolmogorov turbulence and $1/12^circ$ Gulf of Mexico ocean reanalysis, these methods resolve spectral collapse, stabilize long-horizon autoregression, and restore physically realistic inertial-range scaling. Together, they show that na”ive Gaussian scheduling is structurally incompatible with power-law physics and that physics-aware diffusion processes can yield accurate, efficient, and fully probabilistic surrogates for multiscale dynamical systems.
Mucin-type O-glycans regulate proteoglycan stability and chondrocyte maturation
O-glycosylation is a ubiquitous post-translational modification essential for protein stability, cell signaling, and tissue organization, yet how distinct O-glycan subclasses coordinate tissue development remains unclear.



