arXiv:2604.21209v1 Announce Type: new
Abstract: Online reviews have played a pivotal role in consumers’ decision-making processes. Existing research has highlighted the significant impact of managerial review responses on customer relationship management and firm performance. However, a large portion of online reviews remains unaddressed due to the considerable human labor required to respond to the rapid growth of online reviews. While generative AI has achieved remarkable success in a range of tasks, they are general-purpose models and may not align well with domain-specific human preferences. To tailor these general generative AI models to domain-specific applications, finetuning is commonly employed. Nevertheless, several challenges persist in finetuning with domain-specific data, including hallucinations, difficulty in representing domain-specific human preferences, and over conservatism in offline policy optimization. To address these challenges, we propose a novel preference finetuning method to align an LLM with domain-specific human preferences for generating online review responses. Specifically, we first identify the source of hallucination and propose an effective context augmentation approach to mitigate the LLM hallucination. To represent human preferences, we propose a novel theory-driven preference finetuning approach that automatically constructs human preference pairs in the online review domain. Additionally, we propose a curriculum learning approach to further enhance preference finetuning. To overcome the challenge of over conservatism in existing offline preference finetuning method, we propose a novel density estimation-based support constraint method to relax the conservatism, and we mathematically prove its superior theoretical guarantees. Extensive evaluations substantiate the superiority of our proposed preference finetuning method.
Coordinated Temporal Dynamics of Glucocorticoid Receptor Binding and Chromatin Landscape Drive Transcriptional Regulation
Glucocorticoid receptor (GR) signaling elicits diverse transcriptional responses through dynamic and context-dependent interactions with chromatin. Here, we define a temporally resolved and mechanistically integrated framework

