arXiv:2601.05858v2 Announce Type: replace-cross
Abstract: Large language models (LLMs) have demonstrated competitive performance in zero-shot multilingual machine translation (MT). Some follow-up works further improved MT performance via preference optimization, but they leave a key aspect largely underexplored: the order in which data samples are given during training. We address this topic by integrating curriculum learning into various state-of-the-art preference optimization algorithms to boost MT performance. We introduce a novel curriculum learning strategy with restarts (CLewR), which reiterates easy-to-hard curriculum multiple times during training to effectively mitigate the catastrophic forgetting of easy examples. We demonstrate consistent gains across several model families (Gemma2, Qwen2.5, Llama3.1) and preference optimization techniques. We publicly release our code at https://github.com/alexandra-dragomir/CLewR.
Coordinated Temporal Dynamics of Glucocorticoid Receptor Binding and Chromatin Landscape Drive Transcriptional Regulation
Glucocorticoid receptor (GR) signaling elicits diverse transcriptional responses through dynamic and context-dependent interactions with chromatin. Here, we define a temporally resolved and mechanistically integrated framework

