arXiv:2511.16923v1 Announce Type: cross
Abstract: Single-cell RNA sequencing (scRNA-seq) enables transcriptomic profiling at cellular resolution but suffers from pervasive dropout events that obscure biological signals. We present SCR-MF, a modular two-stage workflow that combines principled dropout detection using scRecover with robust non-parametric imputation via missForest. Across public and simulated datasets, SCR-MF achieves robust and interpretable performance comparable to or exceeding existing imputation methods in most cases, while preserving biological fidelity and transparency. Runtime analysis demonstrates that SCR-MF provides a competitive balance between accuracy and computational efficiency, making it suitable for mid-scale single-cell datasets.
Differential acceptance of a national digital health platform among community and frontline health workers in Cote d’Ivoire: a cross-sectional study
IntroductionMobile-based digital health solutions are critical technologies that play a significant role in improving the quality of healthcare services. Cote d’Ivoire is digitizing its community-based