ObjectivesThis study aimed to use the Behaviour Change Wheel (BCW) framework to develop a theory-informed text message intervention (MedText-PCI) to improve medication adherence in patients after percutaneous coronary intervention (PCI).MethodsThis intervention development study was guided by the BCW framework. A behavioural diagnosis was first undertaken to identify barriers and facilitators to medication adherence, which were then mapped onto the Capability, Opportunity, Motivation–Behaviour (COM-B) model. Intervention functions and behaviour change techniques (BCTs) were selected systematically using the APEASE criteria. Based on the selected BCTs, text messages were developed collaboratively by medical experts and a communication specialist.ResultsThe final MedText-PCI intervention comprised 115 theory-informed text messages incorporating 15 distinct BCTs. The messages addressed key domains including treatment benefits, consequences of non-adherence, action planning, and motivational reinforcement. Iterative expert review supported the clinical accuracy, clarity, and accessibility of the intervention content.ConclusionUsing the BCW framework, this study developed a theory-informed text message intervention to support medication adherence after PCI. The development process was systematic and transparent, providing a reproducible basis for future feasibility testing and outcome evaluation. MedText-PCI has the potential to inform adherence support strategies in post-PCI secondary prevention.Clinical Trial Registration:https://www.chictr.org.cn/bin/project/edit?pid=172238, identifier ChiCTR2200061353.
Beyond demographic tables: integrating data quality in clinical trial representativeness
IntroductionClinical trial representativeness is essential for ensuring that study findings generalise to target treatment populations. Current assessment approaches rely on subjective demographic comparisons that lack